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Cell Signal Transduction Research Antibodies
KIF2C Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight81313Da
Protein NameKinesin-like protein KIF2C
Human Gene Id11004
Human Swiss Prot NoQ99661
Mouse Gene Id73804
Mouse Swiss Prot NoQ922S8
SpecificityKIF2C Polyclonal Antibody detects endogenous levels of KIF2C protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKIF2C; KNSL6; Kinesin-like protein KIF2C; Kinesin-like protein 6; Mitotic centromere-associated kinesin; MCAK
Functionfunction:Present throughout the cell cycle, associates with centromeres at early prophase, and remains associated with the centromere until after telophase.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family.,similarity:Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily.,similarity:Contains 1 kinesin-motor domain.,subunit:Interacts with CENPH.,tissue specificity:Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas.,
Subcellular Locationchromosome, centromeric region,kinetochore,condensed chromosome kinetochore,nucleus,cytosol,kinesin complex,microtubule,cytoplasmic microtubule,microtubule cytoskeleton,membrane,microtubule plus-end,
ExpressionBrain,Epithelium,Kidney,T-cell,Testis,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human KIF2C. AA range:61-110
Gene NameKIF2C
DilutionImmunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Backgroundkinesin family member 2C(KIF2C) Homo sapiens This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-72471-Conjugate. Price: $485 / Size: 100μl.
E20-72471-FITC$485 / 100μlE20-72471-Biotin$485 / 100μlE20-72471-HRP$485 / 100μlE20-72471-AP$485 / 100μlE20-72471-AF350$485 / 100μlE20-72471-AF405M$485 / 100μlE20-72471-AF488$485 / 100μlE20-72471-AF514$485 / 100μlE20-72471-AF532$485 / 100μlE20-72471-AF555$485 / 100μlE20-72471-AF568$485 / 100μlE20-72471-AF405S$485 / 100μlE20-72471-AF405L$485 / 100μlE20-72471-AF546$485 / 100μlE20-72471-AF594$485 / 100μlE20-72471-AF610$485 / 100μlE20-72471-AF635$485 / 100μlE20-72471-AF647$485 / 100μlE20-72471-AF680$485 / 100μlE20-72471-AF700$485 / 100μlE20-72471-AF750$485 / 100μlE20-72471-AF790$485 / 100μlE20-72471-APC$485 / 100μlE20-72471-PE$485 / 100μlE20-72471-Cy3$485 / 100μlE20-72471-Cy5$485 / 100μlE20-72471-Cy5.5$485 / 100μlE20-72471-Cy7$485 / 100μlE20-72471-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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