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Cell Signal Transduction Research Antibodies

KDEL Receptor 3 Polyclonal Antibody

E20-72463Cite ID: EN0052596DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight25027Da
Protein NameER lumen protein retaining receptor 3
Human Gene Id11015
Human Swiss Prot NoO43731
Mouse Gene Id105785
Mouse Swiss Prot NoQ8R1L4
SpecificityKDEL Receptor 3 Polyclonal Antibody detects endogenous levels of KDEL Receptor 3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKDELR3; ER lumen protein retaining receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor 3
Observed Band(KD)28
Functionfunction:Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L.,similarity:Belongs to the ERD2 family.,
Subcellular LocationGolgi membrane,endoplasmic reticulum membrane,integral component of membrane,transport vesicle,
ExpressionCervix,Kidney,Stomach,Synovial cell,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ERD23. AA range:61-110
Gene NameKDELR3
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
BackgroundKDEL endoplasmic reticulum protein retention receptor 3(KDELR3) Homo sapiens This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alt

Conjugated Antibody

This product is also available conjugated. Format: E20-72463-Conjugate. Price: $485 / Size: 100μl.

E20-72463-FITC$485 / 100μlE20-72463-Biotin$485 / 100μlE20-72463-HRP$485 / 100μlE20-72463-AP$485 / 100μlE20-72463-AF350$485 / 100μlE20-72463-AF405M$485 / 100μlE20-72463-AF488$485 / 100μlE20-72463-AF514$485 / 100μlE20-72463-AF532$485 / 100μlE20-72463-AF555$485 / 100μlE20-72463-AF568$485 / 100μlE20-72463-AF405S$485 / 100μlE20-72463-AF405L$485 / 100μlE20-72463-AF546$485 / 100μlE20-72463-AF594$485 / 100μlE20-72463-AF610$485 / 100μlE20-72463-AF635$485 / 100μlE20-72463-AF647$485 / 100μlE20-72463-AF680$485 / 100μlE20-72463-AF700$485 / 100μlE20-72463-AF750$485 / 100μlE20-72463-AF790$485 / 100μlE20-72463-APC$485 / 100μlE20-72463-PE$485 / 100μlE20-72463-Cy3$485 / 100μlE20-72463-Cy5$485 / 100μlE20-72463-Cy5.5$485 / 100μlE20-72463-Cy7$485 / 100μlE20-72463-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.