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Cell Signal Transduction Research Antibodies

K-cadherin Polyclonal Antibody

E20-72451Cite ID: EN0052584DatasheetCOAMSDS
Human;Mouse;Rat
WB;IHC-p;IF(paraffin section);ELISA
Polyclonal, Rabbit,IgG
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight88309Da
Protein NameCadherin-6
Human Gene Id1004
Human Swiss Prot NoP55285
Mouse Gene Id12563
Mouse Swiss Prot NoP97326
Rat Gene Id25409
Rat Swiss Prot NoP55280
SpecificityK-cadherin Polyclonal Antibody detects endogenous levels of K-cadherin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDH6; Cadherin-6; Kidney cadherin; K-cadherin
Observed Band(KD)88
Functionfunction:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.,
Subcellular LocationCell membrane; Single-pass type I membrane protein.
ExpressionHighly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from K-cadherin . at AA range: 180-260
Gene NameCDH6
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
BackgroundThis gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011],

Conjugated Antibody

This product is also available conjugated. Format: E20-72451-Conjugate. Price: $485 / Size: 100μl.

E20-72451-FITC$485 / 100μlE20-72451-Biotin$485 / 100μlE20-72451-HRP$485 / 100μlE20-72451-AP$485 / 100μlE20-72451-AF350$485 / 100μlE20-72451-AF405M$485 / 100μlE20-72451-AF488$485 / 100μlE20-72451-AF514$485 / 100μlE20-72451-AF532$485 / 100μlE20-72451-AF555$485 / 100μlE20-72451-AF568$485 / 100μlE20-72451-AF405S$485 / 100μlE20-72451-AF405L$485 / 100μlE20-72451-AF546$485 / 100μlE20-72451-AF594$485 / 100μlE20-72451-AF610$485 / 100μlE20-72451-AF635$485 / 100μlE20-72451-AF647$485 / 100μlE20-72451-AF680$485 / 100μlE20-72451-AF700$485 / 100μlE20-72451-AF750$485 / 100μlE20-72451-AF790$485 / 100μlE20-72451-APC$485 / 100μlE20-72451-PE$485 / 100μlE20-72451-Cy3$485 / 100μlE20-72451-Cy5$485 / 100μlE20-72451-Cy5.5$485 / 100μlE20-72451-Cy7$485 / 100μlE20-72451-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.