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IPP-2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72385Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PPP1R2. AA range:10-59Source:
Polyclonal, RabbitGene Name:
PPP1R2Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
- Western blot analysis of lysates from HUVEC, HepG2, and COLO cells, using PPP1R2 Antibody. The lane on the right is blocked with the synthesized peptide.
Background:
protein phosphatase 1 regulatory inhibitor subunit 2(PPP1R2) Homo sapiens Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],Protein Name:
Protein phosphatase inhibitor 2Human Gene Id:
5504Human Swiss Prot No:
P41236Mouse Gene Id:
66849Mouse Swiss Prot No:
Q9DCL8Rat Gene Id:
192361Rat Swiss Prot No:
P50411Specificity:
IPP-2 Polyclonal Antibody detects endogenous levels of IPP-2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PPP1R2; IPP2; Protein phosphatase inhibitor 2; IPP-2MolecularWeight(Da):
23015Observed Band(KD):
44Function:
function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1.,Subcellular Location:
protein phosphatase type 1 complex,Expression:
Epithelium,Heart,Platelet,Skin,Testis,
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