Catalog Number:
E20-72353Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
Synthesized peptide derived from InsP 3-kinase B . at AA range: 130-210Source:
Polyclonal, RabbitGene Name:
ITPKBDilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.Background:
inositol-trisphosphate 3-kinase B(ITPKB) Homo sapiens The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008],Protein Name:
Inositol-trisphosphate 3-kinase BHuman Gene Id:
3707Human Swiss Prot No:
P27987Rat Gene Id:
54260Rat Swiss Prot No:
P42335Specificity:
InsP 3-kinase B Polyclonal Antibody detects endogenous levels of InsP 3-kinase B protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ITPKB; Inositol-trisphosphate 3-kinase B; Inositol 1; 4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase BMolecularWeight(Da):
102376Observed Band(KD):
100Function:
catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.,enzyme regulation:IP3K is activated by calmodulin. Form B is much more sensitive to calcium/calmodulin than form A.,similarity:Belongs to the inositol phosphokinase (IPK) family.,Subcellular Location:
nucleus,cytosol,membrane,Expression:
Brain,Cerebellum,Colon,Hippocampus,Platelet,Skin,Catalog Number:
E011009-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
145$
Catalog Number:
E011009-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
IHC: 1:50~1:100Swiss-Prot No.:
P60484Price:
225$
Catalog Number:
E011013-1Amount:
50μg/50μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
145$
Catalog Number:
E011013-2Amount:
100μg/100μlReactivity:
Human, Mouse, RatApplications:
WB: 1:500~1:1000 IF:1:100~1:200Swiss-Prot No.:
Q04206Price:
225$
Catalog Number:
E011020-1Amount:
50μg/50μlReactivity:
HumanApplications:
IF:1:100~1:200Swiss-Prot No.:
Q04864Price:
145$