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IL-2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72323

  • Amount:

    100ul

  • Molecular Weight:

    17628Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human IL-2. AA range:16-65

  • Source:

    Polyclonal, Rabbit,IgG

  • Immunofluorescence analysis of A549. 1,primary Antibody(red) was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.

  • Gene Name:

    IL2

  • Dilution:

    Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

  • Protein Name:

    Interleukin-2

  • Human Gene Id:

    3558

  • Human Swiss Prot No:

    P60568

  • Mouse Swiss Prot No:

    P04351

  • Rat Gene Id:

    116562

  • Rat Swiss Prot No:

    P17108

  • Specificity:

    IL-2 Polyclonal Antibody detects endogenous levels of IL-2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    IL2; Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin

  • Observed Band(KD):

    15

  • Background:

    The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008],

  • Function:

    disease:A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.,function:Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.,online information:Interleukin-2 entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the name Proleukin (Chiron). Used in patients with renal cell carcinoma or metastatic melanoma.,similarity:Belongs to the IL-2 family.,

  • Subcellular Location:

    Secreted.

  • Expression:

    Blood,PCR rescued clones,Placenta,Spleen,Products Images

  • Western Blot analysis of various cells using IL-2 Polyclonal Antibody

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Catalog Number

  • Amount:100ul
  • Price:225$

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IL-2 Polyclonal Antibody | EnoGene Biotech Co. Ltd