IGF2-BP2 Polyclonal Antibody

Name: IGF2-BP2 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-72284
Price: 225 USD
Availability: InStock

E20-72284Cite ID: EN0052417Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight61842Da

Protein NameInsulin-like growth factor 2 mRNA-binding protein 2

Human Gene Id10644

Human Swiss Prot NoQ9Y6M1

Mouse Swiss Prot NoQ5SF07

SpecificityIGF2-BP2 Polyclonal Antibody detects endogenous levels of IGF2-BP2 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameIGF2BP2; IMP2; VICKZ2; Insulin-like growth factor 2 mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IMP-2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2

Observed Band(KD)65

Functiondisease:Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.,function:Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs.,similarity:Belongs to the RRM IMP/VICKZ family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,similarity:Contains 4 KH domains.,subcellular location:Localizes at the connecting piece and the tail of the spermatozoa.,subunit:Interacts with HNRPD.,tissue specificity:Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitia

Subcellular Locationnucleus,cytoplasm,cytosol,cytoskeleton,

ExpressionColon adenocarcinoma,Pancreas,Pancreatic islet,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human IGF2BP2. AA range:141-190

Gene NameIGF2BP2

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundinsulin like growth factor 2 mRNA binding protein 2(IGF2BP2) Homo sapiens This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-72284-Conjugate. Price: $485 / Size: 100μl.

E20-72284-FITC$485 / 100μlE20-72284-Biotin$485 / 100μlE20-72284-HRP$485 / 100μlE20-72284-AP$485 / 100μlE20-72284-AF350$485 / 100μlE20-72284-AF405M$485 / 100μlE20-72284-AF488$485 / 100μlE20-72284-AF514$485 / 100μlE20-72284-AF532$485 / 100μlE20-72284-AF555$485 / 100μlE20-72284-AF568$485 / 100μlE20-72284-AF405S$485 / 100μlE20-72284-AF405L$485 / 100μlE20-72284-AF546$485 / 100μlE20-72284-AF594$485 / 100μlE20-72284-AF610$485 / 100μlE20-72284-AF635$485 / 100μlE20-72284-AF647$485 / 100μlE20-72284-AF680$485 / 100μlE20-72284-AF700$485 / 100μlE20-72284-AF750$485 / 100μlE20-72284-AF790$485 / 100μlE20-72284-APC$485 / 100μlE20-72284-PE$485 / 100μlE20-72284-Cy3$485 / 100μlE20-72284-Cy5$485 / 100μlE20-72284-Cy5.5$485 / 100μlE20-72284-Cy7$485 / 100μlE20-72284-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.