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ICAM-2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72270

  • Amount:

    100ul

  • Molecular Weight:

    30654Da

  • Applications:

    WB;ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human ICAM2. AA range:151-200

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of 3T3 cells using ICAM-2 Polyclonal Antibody

  • Gene Name:

    ICAM2

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

  • Background:

    intercellular adhesion molecule 2(ICAM2) Homo sapiens The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Intercellular adhesion molecule 2

  • Human Gene Id:

    3384

  • Human Swiss Prot No:

    P13598

  • Mouse Swiss Prot No:

    P35330

  • Specificity:

    ICAM-2 Polyclonal Antibody detects endogenous levels of ICAM-2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    ICAM2; Intercellular adhesion molecule 2; ICAM-2; CD antigen CD102

  • Observed Band(KD):

    30

  • Function:

    function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.,online information:ICAM-2,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,

  • Subcellular Location:

    Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Co-localizes with RDX, EZR and MSN in microvilli. .

  • Expression:

    Aorta endothelial cell,Blood,Brain,Endothelial cell,Plasma,Spleen,

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Catalog Number

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