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HSP A9 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72246Amount:
100ulMolecular Weight:
73680/73854DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human GRP75. AA range:630-679Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using HSP A9 Polyclonal Antibody diluted at 1:2000
Gene Name:
HSPA9Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Stress-70 protein mitochondrialHuman Gene Id:
3313Human Swiss Prot No:
P38646/Q8N1C8Mouse Gene Id:
15526Rat Gene Id:
291671Rat Swiss Prot No:
P48721Specificity:
HSP A9 Polyclonal Antibody detects endogenous levels of HSP A9 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
HSPA9; GRP75; HSPA9B; Stress-70 protein; mitochondrial; 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74Observed Band(KD):
75Background:
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010],Function:
function:Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with FXN.,Subcellular Location:
Mitochondrion . Nucleus, nucleolus .Expression:
B-cell,Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain.
- Western Blot analysis of COS7 cells using HSP A9 Polyclonal Antibody diluted at 1:2000
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