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HORMAD1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72207Amount:
100ulMolecular Weight:
45200DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human HORMAD1. AA range:321-370Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using HORMAD1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Gene Name:
HORMAD1Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
HORMA domain-containing protein 1Human Gene Id:
84072Human Swiss Prot No:
Q86X24Mouse Swiss Prot No:
Q9D5T7Specificity:
HORMAD1 Polyclonal Antibody detects endogenous levels of HORMAD1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
HORMAD1; NOHMA; HORMA domain-containing protein 1; Cancer/testis antigen 46; CT46; Newborn ovary HORMA proteinObserved Band(KD):
45Background:
This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],Function:
similarity:Contains 1 HORMA domain.,tissue specificity:Testis-specific. Over-expressed in carcinomas.,Subcellular Location:
Nucleus . Chromosome . Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to unsynapsed chromosomal regions (By similarity). .Expression:
Testis-specific. Over-expressed in carcinomas.
- Western blot analysis of lysates from HeLa, HUVEC, and COLO cells, using HORMAD1 Antibody. The lane on the right is blocked with the synthesized peptide.
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