Histone H1 Polyclonal Antibody Antibody

Name: Histone H1 Polyclonal Antibody Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-72151
Price: 225 USD
Availability: InStock

E20-72151Cite ID: EN0052284Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight21010Da

Protein NameHistone H1oo

Human Gene Id132243

Human Swiss Prot NoQ8IZA3

Mouse Swiss Prot NoQ8VIK3

SpecificityHistone H1 Polyclonal Antibody detects endogenous levels of Histone H1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameH1FOO; H1OO; OSH1; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1

Functionfunction:May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.,similarity:Belongs to the histone H1/H5 family.,tissue specificity:Oocyte-specific.,

Subcellular Locationnucleosome,nucleus,nucleolus,cytoplasm,extracellular exosome,

ExpressionBrain,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human Histone H1. AA range:131-180

Gene NameH1FOO

DilutionImmunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

BackgroundH1 histone family member O, oocyte specific(H1FOO) Homo sapiens Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes. [provided by RefSeq, Oct 2015],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-72151-Conjugate. Price: $485 / Size: 100μl.

E20-72151-FITC$485 / 100μlE20-72151-Biotin$485 / 100μlE20-72151-HRP$485 / 100μlE20-72151-AP$485 / 100μlE20-72151-AF350$485 / 100μlE20-72151-AF405M$485 / 100μlE20-72151-AF488$485 / 100μlE20-72151-AF514$485 / 100μlE20-72151-AF532$485 / 100μlE20-72151-AF555$485 / 100μlE20-72151-AF568$485 / 100μlE20-72151-AF405S$485 / 100μlE20-72151-AF405L$485 / 100μlE20-72151-AF546$485 / 100μlE20-72151-AF594$485 / 100μlE20-72151-AF610$485 / 100μlE20-72151-AF635$485 / 100μlE20-72151-AF647$485 / 100μlE20-72151-AF680$485 / 100μlE20-72151-AF700$485 / 100μlE20-72151-AF750$485 / 100μlE20-72151-AF790$485 / 100μlE20-72151-APC$485 / 100μlE20-72151-PE$485 / 100μlE20-72151-Cy3$485 / 100μlE20-72151-Cy5$485 / 100μlE20-72151-Cy5.5$485 / 100μlE20-72151-Cy7$485 / 100μlE20-72151-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.