Histamine H3 Receptor Polyclonal Antibody

Name: Histamine H3 Receptor Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-72142
Price: 225 USD
Availability: InStock

E20-72142Cite ID: EN0052275Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight48671DaObserved Band:49KD

Protein NameHistamine H3 receptor

Human Gene Id11255

Human Swiss Prot NoQ9Y5N1

Mouse Gene Id99296

Mouse Swiss Prot NoP58406

Rat Gene Id85268

Rat Swiss Prot NoQ9QYN8

SpecificityHistamine H3 Receptor Polyclonal Antibody detects endogenous levels of Histamine H3 Receptor protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameHRH3; GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97

Functionalternative products:Additional isoforms seem to exist,function:The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 niether modified adenylate cyclase activity nor induced intracellular calcium mobilization.,miscellaneous:Does not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R(-)-alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various is

Subcellular Locationplasma membrane,integral component of plasma membrane,integral component of membrane,presynapse,

ExpressionBlood,Hippocampus,Thalamus,,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human HRH3. AA range:291-340

Gene NameHRH3

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Backgroundhistamine receptor H3(HRH3) Homo sapiens Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-72142-Conjugate. Price: $485 / Size: 100μl.

E20-72142-FITC$485 / 100μlE20-72142-Biotin$485 / 100μlE20-72142-HRP$485 / 100μlE20-72142-AP$485 / 100μlE20-72142-AF350$485 / 100μlE20-72142-AF405M$485 / 100μlE20-72142-AF488$485 / 100μlE20-72142-AF514$485 / 100μlE20-72142-AF532$485 / 100μlE20-72142-AF555$485 / 100μlE20-72142-AF568$485 / 100μlE20-72142-AF405S$485 / 100μlE20-72142-AF405L$485 / 100μlE20-72142-AF546$485 / 100μlE20-72142-AF594$485 / 100μlE20-72142-AF610$485 / 100μlE20-72142-AF635$485 / 100μlE20-72142-AF647$485 / 100μlE20-72142-AF680$485 / 100μlE20-72142-AF700$485 / 100μlE20-72142-AF750$485 / 100μlE20-72142-AF790$485 / 100μlE20-72142-APC$485 / 100μlE20-72142-PE$485 / 100μlE20-72142-Cy3$485 / 100μlE20-72142-Cy5$485 / 100μlE20-72142-Cy5.5$485 / 100μlE20-72142-Cy7$485 / 100μlE20-72142-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.