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HIPK4 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72137Amount:
100ulMolecular Weight:
69425DaApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Mouse; RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human HIPK4. AA range:511-560Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using HIPK4 Polyclonal Antibody
Gene Name:
HIPK4Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Homeodomain-interacting protein kinase 4Human Gene Id:
147746Human Swiss Prot No:
Q8NE63Mouse Gene Id:
233020Mouse Swiss Prot No:
Q3V016Rat Gene Id:
308449Rat Swiss Prot No:
Q4V793Specificity:
HIPK4 Polyclonal Antibody detects endogenous levels of HIPK4 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
HIPK4; Homeodomain-interacting protein kinase 4Observed Band(KD):
70Background:
homeodomain interacting protein kinase 4(HIPK4) Homo sapiens This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016],Function:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors .,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.,similarity:Contains 1 protein kinase domain.,Subcellular Location:
Cytoplasm .Expression:
Testis,
- Immunofluorescence analysis of A549 cells, using HIPK4 Antibody. The picture on the right is blocked with the synthesized peptide.
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