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Cell Signal Transduction Research Antibodies
Hexim1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight40623 Da
Protein NameProtein HEXIM1
Human Gene Id10614
Human Swiss Prot NoO94992
Mouse Gene Id192231
Mouse Swiss Prot NoQ8R409
Rat Gene Id498008
Rat Swiss Prot NoQ5M9G1
SpecificityHexim1 Polyclonal Antibody detects endogenous levels of Hexim1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameHEXIM1; CLP1; EDG1; HIS1; MAQ1; Protein HEXIM1; Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; Hexamethylene bis-acetamide-inducible protein 1; Menage a quatre protein 1
Observed Band(KD)40
Functiondomain:The coiled-coil domain mediates oligomerization.,function:Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.,induction:Up-regulated by HMBA (hexamethylene bisacetamide) (at protein level). Down-regulated by estrogen.,miscellaneous:Inhibits Tat activity which is required for HIV-1 transcription.,similarity:Belongs to the HEXIM family.,subcellular location:Binds alpha-importin and is mostly nuclear.,subunit:Homooligomer and heterooligomer with HEXIM2; probably dimeric. Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, H
Subcellular Locationnucleus,nucleoplasm,cytoplasm,
ExpressionEpithelium,Lung,Pericardium,Vascular smooth muscle,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human HEXIM1. AA range:181-230
Gene NameHEXIM1
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundhexamethylene bisacetamide inducible 1(HEXIM1) Homo sapiens Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-72129-Conjugate. Price: $485 / Size: 100μl.
E20-72129-FITC$485 / 100μlE20-72129-Biotin$485 / 100μlE20-72129-HRP$485 / 100μlE20-72129-AP$485 / 100μlE20-72129-AF350$485 / 100μlE20-72129-AF405M$485 / 100μlE20-72129-AF488$485 / 100μlE20-72129-AF514$485 / 100μlE20-72129-AF532$485 / 100μlE20-72129-AF555$485 / 100μlE20-72129-AF568$485 / 100μlE20-72129-AF405S$485 / 100μlE20-72129-AF405L$485 / 100μlE20-72129-AF546$485 / 100μlE20-72129-AF594$485 / 100μlE20-72129-AF610$485 / 100μlE20-72129-AF635$485 / 100μlE20-72129-AF647$485 / 100μlE20-72129-AF680$485 / 100μlE20-72129-AF700$485 / 100μlE20-72129-AF750$485 / 100μlE20-72129-AF790$485 / 100μlE20-72129-APC$485 / 100μlE20-72129-PE$485 / 100μlE20-72129-Cy3$485 / 100μlE20-72129-Cy5$485 / 100μlE20-72129-Cy5.5$485 / 100μlE20-72129-Cy7$485 / 100μlE20-72129-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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