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Cell Signal Transduction Research Antibodies
Gβ 5 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight43566Da
Protein NameGuanine nucleotide-binding protein subunit beta-5
Human Gene Id10681
Human Swiss Prot NoO14775
Mouse Gene Id14697
Mouse Swiss Prot NoP62881
Rat Gene Id83579
Rat Swiss Prot NoP62882
SpecificityGβ 5 Polyclonal Antibody detects endogenous levels of Gβ 5 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGNB5; Guanine nucleotide-binding protein subunit beta-5; Gbeta5; Transducin beta chain 5
Observed Band(KD)40
Functionfunction:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the WD repeat G protein beta family.,similarity:Contains 7 WD repeats.,subunit:G proteins are composed of 3 units, alpha, beta and gamma. Component of the RGS9-1-Gbeta5 complex composed of RGS9 (isoform RGS9-1), Gbeta5 (GNB5) and RGS9BP.,tissue specificity:Expressed in multiple tissues.,
Subcellular Locationphotoreceptor outer segment,photoreceptor inner segment,nucleus,cytosol,plasma membrane,myelin sheath,
ExpressionLymph,Muscle,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human GNB5. AA range:151-200
Gene NameGNB5
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
BackgroundG protein subunit beta 5(GNB5) Homo sapiens Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-72096-Conjugate. Price: $485 / Size: 100μl.
E20-72096-FITC$485 / 100μlE20-72096-Biotin$485 / 100μlE20-72096-HRP$485 / 100μlE20-72096-AP$485 / 100μlE20-72096-AF350$485 / 100μlE20-72096-AF405M$485 / 100μlE20-72096-AF488$485 / 100μlE20-72096-AF514$485 / 100μlE20-72096-AF532$485 / 100μlE20-72096-AF555$485 / 100μlE20-72096-AF568$485 / 100μlE20-72096-AF405S$485 / 100μlE20-72096-AF405L$485 / 100μlE20-72096-AF546$485 / 100μlE20-72096-AF594$485 / 100μlE20-72096-AF610$485 / 100μlE20-72096-AF635$485 / 100μlE20-72096-AF647$485 / 100μlE20-72096-AF680$485 / 100μlE20-72096-AF700$485 / 100μlE20-72096-AF750$485 / 100μlE20-72096-AF790$485 / 100μlE20-72096-APC$485 / 100μlE20-72096-PE$485 / 100μlE20-72096-Cy3$485 / 100μlE20-72096-Cy5$485 / 100μlE20-72096-Cy5.5$485 / 100μlE20-72096-Cy7$485 / 100μlE20-72096-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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