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GPRC5B Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72037

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human GPRC5B. AA range:61-110

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    GPRC5B

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Immunofluorescence analysis of MCF7 cells, using GPRC5B Antibody. The picture on the right is blocked with the synthesized peptide.

  • Background:

    G protein-coupled receptor class C group 5 member B(GPRC5B) Homo sapiens This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],

  • Protein Name:

    G-protein coupled receptor family C group 5 member B

  • Human Gene Id:

    51704

  • Human Swiss Prot No:

    Q9NZH0

  • Mouse Swiss Prot No:

    Q923Z0

  • Specificity:

    GPRC5B Polyclonal Antibody detects endogenous levels of GPRC5B protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    GPRC5B; RAIG2; G-protein coupled receptor family C group 5 member B; A-69G12.1; Retinoic acid-induced gene 2 protein; RAIG-2

  • MolecularWeight(Da):

    44795

  • Observed Band(KD):

    48

  • Function:

    caution:It is uncertain whether Met-1 or Met-9 is the initiator.,function:Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.,induction:By all-trans retinoic acid (ATRA).,similarity:Belongs to the G-protein coupled receptor 3 family.,subcellular location:Localized in the plasma membrane and perinuclear vesicles.,tissue specificity:Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465: highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as

  • Subcellular Location:

    extracellular space,nucleus,nucleolus,plasma membrane,cell surface,integral component of membrane,cytoplasmic vesicle membrane,intracellular membrane-bounded organelle,membrane raft,extracellular exosome,

  • Expression:

    Brain,Placenta,Testis,

  • Western blot analysis of lysates from Jurkat, HUVEC, and 293 cells, using GPRC5B Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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GPRC5B Polyclonal Antibody | EnoGene Biotech Co. Ltd