Catalog Number:
E20-71991Amount:
100ulGene Name:
:GPR17Protein Name:
:Uracil nucleotide/cysteinyl leukotriene receptorHuman Gene Id:
:2840Human Swiss Prot No:
:Q13304Mouse Swiss Prot No:
:Q6NS65Immunogen:
:The antiserum was produced against synthesized peptide derived from human GPR17. AA range:221-270Specificity:
:GPR17 Polyclonal Antibody detects endogenous levels of GPR17 protein.Formulation:
:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Source:
:Polyclonal, RabbitDilution:
:Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.Purification:
:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Concentration:
:1 mg/mlStorage Stability:
:-20°C/1 yearOther Name:
:GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12MolecularWeight(Da):
:40989Observed Band(KD):
:40Background:
:function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,Function:
:function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,Subcellular Location:
:plasma membrane,integral component of plasma membrane,integral component of membrane,Expression:
:Brain,Hippocampus,Human cerebellum,Kidney,
Price:
225$