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GPR126 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71967

  • Amount:

    100ul

  • Molecular Weight:

    136636Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human GPR126. AA range:431-480

  • Source:

    Polyclonal, Rabbit,IgG

  • Gene Name:

    GPR126

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Protein Name:

    G-protein coupled receptor 126

  • Human Gene Id:

    57211

  • Human Swiss Prot No:

    Q86SQ4

  • Mouse Swiss Prot No:

    Q6F3F9

  • Specificity:

    GPR126 Polyclonal Antibody detects endogenous levels of GPR126 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    GPR126; DREG; VIGR; G-protein coupled receptor 126; Developmentally regulated G-protein-coupled receptor; Vascular inducible G protein-coupled receptor

  • Observed Band(KD):

    145

  • Background:

    This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009],

  • Function:

    function:Orphan receptor.,polymorphism:Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM:606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 1 pentaxin domain.,

  • Subcellular Location:

    Cell membrane ; Multi-pass membrane protein . Detected on the cell surface of activated but not resting umbilical vein. .

  • Expression:

    Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.

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Catalog Number

  • Amount:100ul
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