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GPR119 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71962Amount:
100ulMolecular Weight:
36889DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human GPR119. AA range:186-235Source:
Polyclonal, Rabbit
- Western Blot analysis of COLO cells using GPR119 Polyclonal Antibody diluted at 1:1000
Gene Name:
GPR119Dilution:
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
Glucose-dependent insulinotropic receptorHuman Gene Id:
139760Human Swiss Prot No:
Q8TDV5Mouse Swiss Prot No:
Q7TQP3Specificity:
GPR119 Polyclonal Antibody detects endogenous levels of GPR119 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
GPR119; Glucose-dependent insulinotropic receptor; G-protein coupled receptor 119Observed Band(KD):
37Background:
G protein-coupled receptor 119(GPR119) Homo sapiens This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010],Function:
function:Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Predominantly expressed in the pancreas, especially in the islets.,Subcellular Location:
plasma membrane,integral component of membrane,receptor complex,
- Western blot analysis of SH-SY5Y mouse-kidney lysis using GPR119 antibody. Antibody was diluted at 1:1000
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