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GPR105 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71952

  • Amount:

    100ul

  • Molecular Weight:

    38971Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human GPR105. AA range:146-195

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using GPR105 Polyclonal Antibody

  • Gene Name:

    P2RY14

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    P2Y purinoceptor 14

  • Human Gene Id:

    9934

  • Human Swiss Prot No:

    Q15391

  • Mouse Gene Id:

    140795

  • Mouse Swiss Prot No:

    Q9ESG6

  • Rat Gene Id:

    171108

  • Rat Swiss Prot No:

    O35881

  • Specificity:

    GPR105 Polyclonal Antibody detects endogenous levels of GPR105 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    P2RY14; GPR105; KIAA0001; P2Y purinoceptor 14; P2Y14; G-protein coupled receptor 105; UDP-glucose receptor

  • Observed Band(KD):

    39

  • Background:

    The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],

  • Function:

    function:Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.,

  • Subcellular Location:

    Cell membrane; Multi-pass membrane protein.

  • Expression:

    Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.

  • Immunofluorescence analysis of MCF7 cells, using GPR105 Antibody. The picture on the right is blocked with the synthesized peptide.

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