Product Information
Molecular Weight55253Da
Protein NameGlycerate kinase
Human Gene Id132158
Human Swiss Prot NoQ8IVS8
Mouse Gene Id235582
Mouse Swiss Prot NoQ8QZY2
Rat Gene Id684314
Rat Swiss Prot NoQ0VGK3
SpecificityGlycerate Kinase Polyclonal Antibody detects endogenous levels of Glycerate Kinase protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGLYCTK; HBEBP4; LP5910; Glycerate kinase; HBeAg-binding protein 4
Observed Band(KD)60
Functioncatalytic activity:ATP + (R)-glycerate = ADP + 3-phospho-(R)-glycerate.,disease:Defects in GLYCTK are the cause of D-glyceric acidemia [MIM:220120]. It is characterized by nonketotic hyperglycinemia with the excretion of D-glyceric acid in the urine and the presence of this substance in the serum.,similarity:Belongs to the glycerate kinase type-2 family.,tissue specificity:Widely expressed.,
Subcellular Locationcytoplasm,mitochondrion,cytosol,
ExpressionLiver,Lung,Skin,
Backgroundglycerate kinase(GLYCTK) Homo sapiens This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],