World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
Gemin3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight92241DaObserved Band:90KD
Protein NameProbable ATP-dependent RNA helicase DDX20
Human Gene Id11218
Human Swiss Prot NoQ9UHI6
Mouse Gene Id53975
Mouse Swiss Prot NoQ9JJY4
SpecificityGemin3 Polyclonal Antibody detects endogenous levels of Gemin3 protein
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDDX20; DP103; GEMIN3; Probable ATP-dependent RNA helicase DDX20; Component of gems 3; DEAD box protein 20; DEAD box protein DP 103; Gemin-3
Functionfunction:The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.,similarity:Belongs to the DEAD box helicase family.,similarity:Belongs to the DEAD box helicase family. DDX20 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subcellular location:Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems).,subunit:Part of the core SMN complex that contains SMN1, SIP1/GEMIN2, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with SMN1 and with several spliceosomal snRNP core Sm proteins, including SNUPN, SNRPB, SNRPD2 and SNRPD3. Interacts with PPP4R2. Interacts with EBV EBNA2 and EBNA3C.,tissue specificity:Ubiquitous.
Subcellular Locationnucleus,nucleoplasm,cytoplasm,cytosol,cytoskeleton,membrane,SMN complex,SMN-Sm protein complex,RNA polymerase II transcription repressor complex,Gemini of coiled bodies,
ExpressionEpithelium,Placenta,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human DDX20. AA range:273-322
Gene NameDDX20
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
BackgroundDEAD-box helicase 20(DDX20) Homo sapiens DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-71893-Conjugate. Price: $485 / Size: 100μl.
E20-71893-FITC$485 / 100μlE20-71893-Biotin$485 / 100μlE20-71893-HRP$485 / 100μlE20-71893-AP$485 / 100μlE20-71893-AF350$485 / 100μlE20-71893-AF405M$485 / 100μlE20-71893-AF488$485 / 100μlE20-71893-AF514$485 / 100μlE20-71893-AF532$485 / 100μlE20-71893-AF555$485 / 100μlE20-71893-AF568$485 / 100μlE20-71893-AF405S$485 / 100μlE20-71893-AF405L$485 / 100μlE20-71893-AF546$485 / 100μlE20-71893-AF594$485 / 100μlE20-71893-AF610$485 / 100μlE20-71893-AF635$485 / 100μlE20-71893-AF647$485 / 100μlE20-71893-AF680$485 / 100μlE20-71893-AF700$485 / 100μlE20-71893-AF750$485 / 100μlE20-71893-AF790$485 / 100μlE20-71893-APC$485 / 100μlE20-71893-PE$485 / 100μlE20-71893-Cy3$485 / 100μlE20-71893-Cy5$485 / 100μlE20-71893-Cy5.5$485 / 100μlE20-71893-Cy7$485 / 100μlE20-71893-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits