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GCP4 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71880

  • Amount:

    100ul

  • Molecular Weight:

    76089DaObserved Band:76KD

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human TUBGCP4. AA range:191-240

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using GCP4 Polyclonal Antibody

  • Gene Name:

    TUBGCP4

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Gamma-tubulin complex component 4

  • Human Gene Id:

    27229

  • Human Swiss Prot No:

    Q9UGJ1

  • Mouse Gene Id:

    51885

  • Mouse Swiss Prot No:

    Q9D4F8

  • Specificity:

    GCP4 Polyclonal Antibody detects endogenous levels of GCP4 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    TUBGCP4; 76P; GCP4; Gamma-tubulin complex component 4; GCP-4; hGCP4; Gamma-ring complex protein 76 kDa; h76p; hGrip76

  • Background:

    This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015],

  • Function:

    function:Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.,similarity:Belongs to the GCP family.,subunit:Gamma-tubulin complex is composed of gamma-tubulin, GCP2, GCP3, GCP4, GCP5 and GCP6.,tissue specificity:Ubiquitously expressed.,

  • Subcellular Location:

    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

  • Expression:

    Ubiquitously expressed.

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Catalog Number

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