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GADD 45γ Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71832

  • Amount:

    100ul

  • Molecular Weight:

    17121Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human GA45G. AA range:101-150

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using GADD 45γ Polyclonal Antibody

  • Gene Name:

    GADD45G

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Protein Name:

    Growth arrest and DNA damage-inducible protein GADD45 gamma

  • Human Gene Id:

    10912

  • Human Swiss Prot No:

    O95257

  • Mouse Swiss Prot No:

    Q9Z111

  • Rat Gene Id:

    291005

  • Rat Swiss Prot No:

    Q9WTQ7

  • Specificity:

    GADD 45γ Polyclonal Antibody detects endogenous levels of GADD 45γ protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    GADD45G; CR6; DDIT2; Growth arrest and DNA damage-inducible protein GADD45 gamma; Cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; DDIT-2

  • Observed Band(KD):

    19

  • Background:

    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008],

  • Function:

    function:Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.,similarity:Belongs to the GADD45 family.,subunit:Interacts with GADD45GIP1.,

  • Subcellular Location:

    nucleus,cytoplasm,

  • Expression:

    Brain,Colon carcinoma,Lung,Placenta,

  • Western blot analysis of GA45G Antibody. The lane on the right is blocked with the GA45G peptide.

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