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GABAA Rα6 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71823

  • Amount:

    100ul

  • Molecular Weight:

    51024Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human GABRA6. AA range:61-110

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500

  • Gene Name:

    GABRA6

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    Gamma-aminobutyric acid receptor subunit alpha-6

  • Human Gene Id:

    2559

  • Human Swiss Prot No:

    Q16445

  • Mouse Gene Id:

    14399

  • Mouse Swiss Prot No:

    P16305

  • Rat Gene Id:

    29708

  • Rat Swiss Prot No:

    P30191

  • Specificity:

    GABAA Rα6 Polyclonal Antibody detects endogenous levels of GABAA Rα6 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    GABRA6; Gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6

  • Observed Band(KD):

    51

  • Background:

    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008],

  • Function:

    function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,online information:Forbidden fruit - Issue 56 of March 2005,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.,

  • Subcellular Location:

    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

  • Expression:

    Cerebellum,

  • Western Blot analysis of MOUSE-BRAIN cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500

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Catalog Number

  • Amount:100ul
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