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Fucokinase Polyclonal Antibody
Datasheet
Catalog Number:
E20-71798Amount:
100ulMolecular Weight:
117623 DaObserved Band:110 KDApplications:
WB;IF/ICC;ELISAReactivity:
Human;Mouse;MonkeyPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human FUK. AA range:11-60Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using Fucokinase Polyclonal Antibody
Gene Name:
FUKDilution:
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
L-fucose kinaseHuman Gene Id:
197258Human Swiss Prot No:
Q8N0W3Specificity:
Fucokinase Polyclonal Antibody detects endogenous levels of Fucokinase protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
FUK; L-fucose kinase; FucokinaseBackground:
fucokinase(FUK) Homo sapiens The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008],Function:
catalytic activity:ATP + L-fucose = ADP + beta-L-fucose 1-phosphate.,function:Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.,similarity:Belongs to the GHMP kinase family.,Subcellular Location:
cytoplasm,cytosol,Expression:
Expressed in fibroblasts.
- Immunofluorescence analysis of NIH/3T3 cells, using FUK Antibody. The picture on the right is blocked with the synthesized peptide.
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