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FRP-2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71790Amount:
100ulMolecular Weight:
33490 DaObserved Band:30 KDApplications:
WB;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human SFRP2. AA range:119-168Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using FRP-2 Polyclonal Antibody diluted at 1:500
Gene Name:
SFRP2Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.Protein Name:
Secreted frizzled-related protein 2Human Gene Id:
6423Human Swiss Prot No:
Q96HF1Mouse Gene Id:
20319Mouse Swiss Prot No:
P97299Specificity:
FRP-2 Polyclonal Antibody detects endogenous levels of FRP-2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
SFRP2; FRP2; SARP1; FKSG12; Secreted frizzled-related protein 2; FRP-2; sFRP-2; Secreted apoptosis-related protein 1; SARP-1Background:
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008],Function:
domain:The FZ domain is involved in binding with Wnt ligands.,function:Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.,similarity:Belongs to the secreted frizzled-related protein (sFRP) family.,similarity:Contains 1 FZ (frizzled) domain.,similarity:Contains 1 NTR domain.,tissue specificity:Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.,Subcellular Location:
Secreted .Expression:
Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
- Western Blot analysis of HuvEc cells using FRP-2 Polyclonal Antibody diluted at 1:500
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