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Fos B Polyclonal Antibody
Datasheet
Catalog Number:
E20-71738Amount:
100ulMolecular Weight:
35928DaApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Mouse;MonkeyPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human FosB. AA range:12-61Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using Fos B Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit
Gene Name:
FOSBDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Protein fosBHuman Gene Id:
2354Human Swiss Prot No:
P53539Mouse Gene Id:
14282Mouse Swiss Prot No:
P13346Specificity:
Fos B Polyclonal Antibody detects endogenous levels of Fos B protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
FOSB; G0S3; Protein fosB; G0/G1 switch regulatory protein 3Observed Band(KD):
35Background:
FosB proto-oncogene, AP-1 transcription factor subunit(FOSB) Homo sapiens The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],Function:
function:FosB interacts with Jun proteins enhancing their DNA binding activity.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,Subcellular Location:
Nucleus .Expression:
[Isoform 11]: Expressed in the nucleus accumbens of the striatum (at protein level).
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