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Fibulin-2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71707

  • Amount:

    100ul

  • Molecular Weight:

    126544Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using Fibulin-2 Polyclonal Antibody diluted at 1:500

  • Gene Name:

    FBLN2

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    Fibulin-2

  • Human Gene Id:

    2199

  • Human Swiss Prot No:

    P98095

  • Mouse Swiss Prot No:

    P37889

  • Specificity:

    Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    FBLN2; Fibulin-2; FIBL-2

  • Observed Band(KD):

    130

  • Background:

    fibulin 2(FBLN2) Homo sapiens This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

  • Function:

    developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,

  • Subcellular Location:

    Secreted, extracellular space, extracellular matrix.

  • Expression:

    Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.

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