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Cell Signal Transduction Research Antibodies
FADD Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight23279Da
Protein NameProtein FADD
Mouse Gene Id14082
SpecificityFADD Polyclonal Antibody detects endogenous levels of FADD protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFADD; MORT1; GIG3; Protein FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity
Observed Band(KD)30
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from FADD . at AA range: 130-210
Gene NameFADD
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
BackgroundThe Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Conjugated Antibody
This product is also available conjugated. Format: E20-71657-Conjugate. Price: $485 / Size: 100μl.
E20-71657-FITC$485 / 100μlE20-71657-Biotin$485 / 100μlE20-71657-HRP$485 / 100μlE20-71657-AP$485 / 100μlE20-71657-AF350$485 / 100μlE20-71657-AF405M$485 / 100μlE20-71657-AF488$485 / 100μlE20-71657-AF514$485 / 100μlE20-71657-AF532$485 / 100μlE20-71657-AF555$485 / 100μlE20-71657-AF568$485 / 100μlE20-71657-AF405S$485 / 100μlE20-71657-AF405L$485 / 100μlE20-71657-AF546$485 / 100μlE20-71657-AF594$485 / 100μlE20-71657-AF610$485 / 100μlE20-71657-AF635$485 / 100μlE20-71657-AF647$485 / 100μlE20-71657-AF680$485 / 100μlE20-71657-AF700$485 / 100μlE20-71657-AF750$485 / 100μlE20-71657-AF790$485 / 100μlE20-71657-APC$485 / 100μlE20-71657-PE$485 / 100μlE20-71657-Cy3$485 / 100μlE20-71657-Cy5$485 / 100μlE20-71657-Cy5.5$485 / 100μlE20-71657-Cy7$485 / 100μlE20-71657-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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- Antibodies
- Tag antibodies
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- Cell Signal Transduction Research Antibodies
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