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ETS1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71644Amount:
100ulMolecular Weight:
50202(DA) Observed Band(KD)50Price:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human ETS1. AA range:11-60Source:
Polyclonal, Rabbit
- Western Blot analysis of 293T cells using ETS1 Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Gene Name:
ETS1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.Protein Name:
Protein C-ets-1Human Gene Id:
2113Human Swiss Prot No:
P14921Mouse Gene Id:
23871Mouse Swiss Prot No:
P27577Rat Gene Id:
24356Rat Swiss Prot No:
P41156Specificity:
ETS1 Polyclonal Antibody detects endogenous levels of ETS1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ETS1; EWSR2; Protein C-ets-1; p54Background:
ETS proto-oncogene 1, transcription factor(ETS1) Homo sapiens This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],Function:
disease:ETS is responsible for erythroblast and fibroblast transformation. The juxtaposition of the interferon and c-ETS-1 proto-oncogene may be involved in the pathogenesis of human monocytic leukemia.,function:Transcription factor.,PTM:Sumoylated on Lys-15 and Lys-227, preferentially by SUMO2; which inhibits transcriptional activity.,PTM:Ubiquitinated; which induces proteasomal degradation.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,similarity:Contains 1 PNT (pointed) domain.,subunit:Interacts with MAF and MAFB (By similarity). Binds to DAXX. Interacts with UBE2I.,Subcellular Location:
nucleus,nucleoplasm,transcription factor complex,cytoplasm,Expression:
Human endometrium,Lung,Synovial membrane tissue
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Catalog Number
- Amount:100ul
- Price:225$
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