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Epsin 3 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71603

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    EPN3

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using EPN3 Antibody. The picture on the right is blocked with the synthesized peptide.

  • Background:

    induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.,

  • Protein Name:

    Epsin-3

  • Human Gene Id:

    55040

  • Human Swiss Prot No:

    Q9H201

  • Mouse Swiss Prot No:

    Q91W69

  • Specificity:

    Epsin 3 Polyclonal Antibody detects endogenous levels of Epsin 3 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    EPN3; Epsin-3; EPS-15-interacting protein 3

  • MolecularWeight(Da):

    68222

  • Observed Band(KD):

    68

  • Function:

    induction:In keratinocytes, by wounding or contact with collagen.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.,tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.,

  • Subcellular Location:

    nucleus,nucleoplasm,clathrin-coated pit,extrinsic component of plasma membrane,clathrin-coated vesicle,intracellular membrane-bounded organelle,perinuclear region of cytoplasm,extracellular exosome,

  • Expression:

    Colon,Placenta,Skin,

  • Western blot analysis of lysates from K562 cells, using EPN3 Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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Epsin 3 Polyclonal Antibody | EnoGene Biotech Co. Ltd