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Epsin 2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71602

  • Amount:

    100ul

  • Molecular Weight:

    68554Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human EPN2. AA range:271-320

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using Epsin 2 Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    EPN2

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Epsin-2

  • Human Gene Id:

    22905

  • Human Swiss Prot No:

    O95208

  • Mouse Gene Id:

    13855

  • Mouse Swiss Prot No:

    Q8CHU3

  • Rat Gene Id:

    60443

  • Rat Swiss Prot No:

    Q9Z1Z3

  • Specificity:

    Epsin 2 Polyclonal Antibody detects endogenous levels of Epsin 2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    EPN2; KIAA1065; Epsin-2; EPS-15-interacting protein 2

  • Observed Band(KD):

    68

  • Background:

    epsin 2(EPN2) Homo sapiens This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

  • Function:

    caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:The DPW repeat domain is involved in AP-2 and clathrin binding.,domain:The NPF repeat domain is involved in EPS15 binding.,function:Plays a role in the formation of clathrin-coated invaginations and endocytosis.,PTM:Ubiquitinated.,similarity:Belongs to the epsin family.,similarity:Contains 1 ENTH (epsin N-terminal homology) domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,subcellular location:In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.,subunit:Binds EPS15 (By similarity). Binds AP-2 and clathrin.,tissue specificity:Highest expression is found in brain. Detected at lower levels in lung and liver.,

  • Subcellular Location:

    Cytoplasm . Cytoplasmic vesicle, clathrin-coated vesicle . In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.

  • Expression:

    Highest expression is found in brain. Detected at lower levels in lung and liver.

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Catalog Number

  • Amount:100ul
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Epsin 2 Polyclonal Antibody | EnoGene Biotech Co. Ltd