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Eps8L2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71599Amount:
100ulMolecular Weight:
80621DaApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human ES8L2. AA range:1-50Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of HuvEc cells using Eps8L2 Polyclonal Antibody
Gene Name:
EPS8L2Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Epidermal growth factor receptor kinase substrate 8-like protein 2Human Gene Id:
64787Human Swiss Prot No:
Q9H6S3Mouse Gene Id:
98845Mouse Swiss Prot No:
Q99K30Specificity:
Eps8L2 Polyclonal Antibody detects endogenous levels of Eps8L2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
EPS8L2; EPS8R2; PP13181; Epidermal growth factor receptor kinase substrate 8-like protein 2; EPS8-like protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8-related protein 2Observed Band(KD):
81Background:
EPS8 like 2(EPS8L2) Homo sapiens This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008],Function:
function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 PID domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in fibroblasts and placenta.,Subcellular Location:
Cytoplasm . Cell projection, stereocilium . Localizes at the tips of the stereocilia of the inner and outer hair cells. .Expression:
Detected in fibroblasts and placenta.
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