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Eps8L1 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71598

  • Amount:

    100ul

  • Molecular Weight:

    80309Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human ES8L1. AA range:411-460

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using Eps8L1 Polyclonal Antibody

  • Gene Name:

    EPS8L1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Epidermal growth factor receptor kinase substrate 8-like protein 1

  • Human Gene Id:

    54869

  • Human Swiss Prot No:

    Q8TE68

  • Mouse Gene Id:

    67425

  • Mouse Swiss Prot No:

    Q8R5F8

  • Specificity:

    Eps8L1 Polyclonal Antibody detects endogenous levels of Eps8L1 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    EPS8L1; DRC3; EPS8R1; PP10566; Epidermal growth factor receptor kinase substrate 8-like protein 1; EPS8-like protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-related protein 1

  • Observed Band(KD):

    80

  • Background:

    This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • Function:

    function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in placenta.,

  • Subcellular Location:

    Cytoplasm .

  • Expression:

    Detected in placenta..

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