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EphA7 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71581Amount:
100ulMolecular Weight:
(:112097(DA) Observed Band(KD)112Price:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human EPHA7. AA range:451-500Source:
Polyclonal, Rabbit
- Western Blot analysis of 293T-UV cells using EphA7 Polyclonal Antibody diluted at 1:500
Gene Name:
EPHA7Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Ephrin type-A receptor 7Human Gene Id:
2045Human Swiss Prot No:
Q15375Mouse Gene Id:
13841Mouse Swiss Prot No:
Q61772Rat Gene Id:
171287Rat Swiss Prot No:
P54759Specificity:
EphA7 Polyclonal Antibody detects endogenous levels of EphA7 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
EPHA7; EHK3; HEK11; Ephrin type-A receptor 7; EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11Background:
EPH receptor A7(EPHA7) Homo sapiens This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],Function:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,subunit:Interacts with PRKCABP and GRIP1.,tissue specificity:Widely expressed.,Subcellular Location:
plasma membrane,integral component of plasma membrane,dendrite,neuromuscular junction,neuronal cell body,postsynaptic membrane,Expression:
Brain,Fetal brain,
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Catalog Number
- Amount:100ul
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