Epac Polyclonal Antibody

Name: Epac Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-71571
Price: 225 USD
Availability: InStock

E20-71571Cite ID: EN0051704Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight99353 Da

Protein NameRap guanine nucleotide exchange factor 3

Human Gene Id10411

Human Swiss Prot NoO95398

Mouse Gene Id223864

Mouse Swiss Prot NoQ8VCC8

Rat Gene Id59326

Rat Swiss Prot NoQ9Z1C8

SpecificityEpac Polyclonal Antibody detects endogenous levels of Epac protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameRAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP;

Observed Band(KD)100

Functioncaution:It is uncertain whether Met-1 or Met-43 is the initiator.,domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 DEP domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.,

Subcellular Locationintracellular,plasma membrane,microvillus,endomembrane system,membrane,lamellipodium,filopodium,cortical actin cytoskeleton,extracellular exosome,

ExpressionBrain,Kidney,Muscle,Peripheral Nervous System,Thalamus,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human RAPGEF3. AA range:712-761

Gene NameRAPGEF3

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Backgroundcaution:It is uncertain whether Met-1 or Met-43 is the initiator.,domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 DEP domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.,

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-71571-Conjugate. Price: $485 / Size: 100μl.

E20-71571-FITC$485 / 100μlE20-71571-Biotin$485 / 100μlE20-71571-HRP$485 / 100μlE20-71571-AP$485 / 100μlE20-71571-AF350$485 / 100μlE20-71571-AF405M$485 / 100μlE20-71571-AF488$485 / 100μlE20-71571-AF514$485 / 100μlE20-71571-AF532$485 / 100μlE20-71571-AF555$485 / 100μlE20-71571-AF568$485 / 100μlE20-71571-AF405S$485 / 100μlE20-71571-AF405L$485 / 100μlE20-71571-AF546$485 / 100μlE20-71571-AF594$485 / 100μlE20-71571-AF610$485 / 100μlE20-71571-AF635$485 / 100μlE20-71571-AF647$485 / 100μlE20-71571-AF680$485 / 100μlE20-71571-AF700$485 / 100μlE20-71571-AF750$485 / 100μlE20-71571-AF790$485 / 100μlE20-71571-APC$485 / 100μlE20-71571-PE$485 / 100μlE20-71571-Cy3$485 / 100μlE20-71571-Cy5$485 / 100μlE20-71571-Cy5.5$485 / 100μlE20-71571-Cy7$485 / 100μlE20-71571-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.