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Endomucin Polyclonal Antibody
Datasheet
Catalog Number:
E20-71557Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human Mucin-14. AA range:201-250Source:
Polyclonal, RabbitGene Name:
EMCNDilution:
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Immunofluorescence analysis of HepG2 cells, using Mucin-14 Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
endomucin(EMCN) Homo sapiens EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008],Protein Name:
EndomucinHuman Gene Id:
51705Human Swiss Prot No:
Q9ULC0Mouse Gene Id:
59308Mouse Swiss Prot No:
Q9R0H2Rat Gene Id:
295490Rat Swiss Prot No:
Q6AY82Specificity:
Endomucin Polyclonal Antibody detects endogenous levels of Endomucin protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
EMCN; EMCN2; MUC14; Endomucin; Endomucin-2; Gastric cancer antigen Ga34; Mucin-14; MUC-14MolecularWeight(Da):
27452Function:
function:Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.,PTM:Highly O-glycosylated. Sialic acid-rich glycoprotein.,subcellular location:Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.,tissue specificity:Expressed in heart, kidney and lung.,Subcellular Location:
extracellular region,plasma membrane,external side of plasma membrane,integral component of membrane,Expression:
Brain,Dermoid cancer,Gastric adenocarcinoma,Lung,Umbilical vein endothelial cell,Uterus,Vascular en,
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