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Egr-2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71498

  • Amount:

    100ul

  • Molecular Weight:

    57507/50302Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human EGR1/2. AA range:371-420

  • Source:

    Polyclonal, Rabbit,IgG

  • Western blot analysis of lysates from HeLa and Jurkat cells, using EGR1/2 Antibody. The lane on the right is blocked with the synthesized peptide.

  • Gene Name:

    EGR2

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Early growth response protein 2

  • Human Gene Id:

    1958/1959

  • Human Swiss Prot No:

    P18146/P11161

  • Mouse Gene Id:

    13653/13654

  • Rat Gene Id:

    24330/114090

  • Rat Swiss Prot No:

    P08154/P51774

  • Specificity:

    Egr-2 Polyclonal Antibody detects endogenous levels of Egr-2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    EGR1; KROX24; ZNF225; Early growth response protein 1; EGR-1; AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24; EGR2; KROX20

  • Observed Band(KD):

    50

  • Background:

    The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014],

  • Function:

    function:Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.,induction:By growth factors.,similarity:Belongs to the EGR C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

  • Subcellular Location:

    Nucleus . Cytoplasm .

  • Expression:

    Detected in neutrophils (at protein level).

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Catalog Number

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