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EDG-5 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71467

  • Amount:

    100ul

  • Molecular Weight:

    38867Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human EDG5. AA range:261-310

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using EDG-5 Polyclonal Antibody

  • Gene Name:

    S1PR2

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Sphingosine 1-phosphate receptor 2

  • Human Gene Id:

    9294

  • Human Swiss Prot No:

    O95136

  • Mouse Gene Id:

    14739

  • Mouse Swiss Prot No:

    P52592

  • Rat Gene Id:

    29415

  • Rat Swiss Prot No:

    P47752

  • Specificity:

    EDG-5 Polyclonal Antibody detects endogenous levels of EDG-5 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    S1PR2; EDG5; Sphingosine 1-phosphate receptor 2; S1P receptor 2; S1P2; Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5

  • Observed Band(KD):

    39

  • Background:

    This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016],

  • Function:

    function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.,similarity:Belongs to the G-protein coupled receptor 1 family.,

  • Subcellular Location:

    Cell membrane; Multi-pass membrane protein.

  • Expression:

    Fetal brain,

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