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EDG-3 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71462

  • Amount:

    100ul

  • Molecular Weight:

    42250Da

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human EDG3. AA range:115-164

  • Source:

    Polyclonal, Rabbit

  • Yuan Chang, Hu, et al. "Hyperglycemia Triggered S1P/S1PR3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization." Chao and Yang, Shikun and Cheng, Xuyu and Cheng, Feng and Rao, Jianhua and Wang, Xue-Hao, Hyperglycemia Triggered S1P/S1PR3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M 1 (2018).

  • Gene Name:

    S1PR3

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    Sphingosine 1-phosphate receptor 3

  • Human Gene Id:

    1903

  • Human Swiss Prot No:

    Q99500

  • Specificity:

    EDG-3 Polyclonal Antibody detects endogenous levels of EDG-3 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    S1PR3; EDG3; Sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3

  • Observed Band(KD):

    42

  • Background:

    sphingosine-1-phosphate receptor 3(S1PR3) Homo sapiens This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008],

  • Function:

    function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.,

  • Subcellular Location:

    plasma membrane,integral component of plasma membrane,

  • Expression:

    Brain,Placenta,Testis,

  • Western Blot analysis of HT-29 cells using EDG-3 Polyclonal Antibody

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Catalog Number

  • Amount:100ul
  • Price:225$

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