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EDG-2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71461

  • Amount:

    100ul

  • Molecular Weight:

    41109Da

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human EDG2. AA range:5-54

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of Jurkat cells using EDG-2 Polyclonal Antibody diluted at 1:500

  • Gene Name:

    LPAR1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Protein Name:

    Lysophosphatidic acid receptor 1

  • Human Gene Id:

    1902

  • Human Swiss Prot No:

    Q92633

  • Specificity:

    EDG-2 Polyclonal Antibody detects endogenous levels of EDG-2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    LPAR1; EDG2; LPA1; Lysophosphatidic acid receptor 1; LPA receptor 1; LPA-1; Lysophosphatidic acid receptor Edg-2

  • Observed Band(KD):

    38

  • Background:

    lysophosphatidic acid receptor 1(LPAR1) Homo sapiens The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008],

  • Function:

    function:Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes.,

  • Subcellular Location:

    cytoplasm,endosome,plasma membrane,integral component of plasma membrane,cell surface,integral component of membrane,endocytic vesicle,neuronal cell body,dendritic spine,dendritic shaft,

  • Expression:

    Brain,Hippocampus,Peripheral Nervous System,Testis,Tongue,

  • Western blot analysis of KB 293T lysis using EDG-2 antibody. Antibody was diluted at 1:500

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Catalog Number

  • Amount:100ul
  • Price:225$

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EDG-2 Polyclonal Antibody | EnoGene Biotech Co. Ltd