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Dvl-2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71424

  • Amount:

    100ul

  • Molecular Weight:

    78948Da

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    Synthesized peptide derived from Dvl-2 . at AA range: 670-750

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of K562 cells using Dvl-2 Polyclonal Antibody

  • Gene Name:

    DVL2

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    Segment polarity protein dishevelled homolog DVL-2

  • Human Gene Id:

    1856

  • Human Swiss Prot No:

    O14641

  • Specificity:

    Dvl-2 Polyclonal Antibody detects endogenous levels of Dvl-2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    DVL2; Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2

  • Observed Band(KD):

    80

  • Background:

    dishevelled segment polarity protein 2(DVL2) Homo sapiens This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008],

  • Function:

    function:May play a role in the signal transduction pathway mediated by multiple Wnt genes.,PTM:Phosphorylated.,similarity:Belongs to the DSH family.,similarity:Contains 1 DEP domain.,similarity:Contains 1 DIX domain.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Interacts through its PDZ domain with the C-terminal regions of VANGL1 and VANGL2 (By similarity). Interacts with DIXDC1 and Rac.,

  • Subcellular Location:

    intracellular,nucleus,cytoplasm,cytosol,plasma membrane,lateral plasma membrane,cytoplasmic vesicle,apical part of cell,clathrin-coated endocytic vesicle,

  • Expression:

    Colon,

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Catalog Number

  • Amount:100ul
  • Price:225$

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