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DRS-1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71415Amount:
100ulMolecular Weight:
39609DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;Rat;Mouse;Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PECI. AA range:73-122Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using DRS-1 Polyclonal Antibody
Gene Name:
ECI2Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Enoyl-CoA delta isomerase 2 mitochondrialHuman Gene Id:
10455Human Swiss Prot No:
O75521Mouse Swiss Prot No:
Q9WUR2Specificity:
DRS-1 Polyclonal Antibody detects endogenous levels of DRS-1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ECI2; DRS1; HCA88; PECI; Enoyl-CoA delta isomerase 2; mitochondrial; DRS-1; Delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; Dodecenoyl-CoA isomerase; HepObserved Band(KD):
40Background:
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011],Function:
catalytic activity:(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.,function:Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.,similarity:Contains 1 ACB (acyl-CoA-binding) domain.,similarity:In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.,tissue specificity:Abundant in heart, skeletal muscle and liver.,Subcellular Location:
[Isoform 1]: Mitochondrion .; [Isoform 2]: Peroxisome matrix .Expression:
Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.
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