Product Information
Protein NameDnaJ homolog subfamily B member 4
Human Gene Id11080
Human Swiss Prot NoQ9UDY4
Mouse Gene Id67035
Mouse Swiss Prot NoQ9D832
SpecificityDnaJB4 Polyclonal Antibody detects endogenous levels of DnaJB4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDNAJB4; DNAJW; HLJ1; DnaJ homolog subfamily B member 4; Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein
Molecular Weight37807Da
Observed Band(KD)38
Functioninduction:By heat shock.,similarity:Contains 1 J domain.,
Subcellular LocationCytoplasm . Cell membrane . Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
ExpressionExpressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.
BackgroundThe protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],