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DHS Polyclonal Antibody
Human;Rat;Mouse;
WB;ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameDHPS
Product Information
Protein NameDeoxyhypusine synthase
Human Gene Id1725
Human Swiss Prot NoP49366
Mouse Swiss Prot NoQ3TXU5
SpecificityDHS Polyclonal Antibody detects endogenous levels of DHS protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDHPS; DS; Deoxyhypusine synthase; DHS
Molecular Weight40971Da
Observed Band(KD)45
Functioncatalytic activity:[eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine.,cofactor:NAD.,function:Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.,pathway:Protein modification; eIF5A hypusination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the deoxyhypusine synthase family.,subunit:Homotetramer formed by a dimer of dimers.,
Subcellular Locationcytoplasm,cytosol,
ExpressionBlood,Brain,Cervix carcinoma,Lung,
ImmunogenThe antiserum was produced against synthesized peptide derived from human DHPS. AA range:51-100
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
BackgroundThis gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011],
Western Blot analysis of K562 cells using Western DHS Polyclonal Antibody. Antibody.
Blot analysis of K562 cells using DHS Polyclonal
Conjugated Antibody
This product is also available conjugated. Format: E20-713850-Conjugate. Price: $485 / Size: 100μl.
E20-713850-FITC$485 / 100μlE20-713850-Biotin$485 / 100μlE20-713850-HRP$485 / 100μlE20-713850-AP$485 / 100μlE20-713850-AF350$485 / 100μlE20-713850-AF405M$485 / 100μlE20-713850-AF488$485 / 100μlE20-713850-AF514$485 / 100μlE20-713850-AF532$485 / 100μlE20-713850-AF555$485 / 100μlE20-713850-AF568$485 / 100μlE20-713850-AF405S$485 / 100μlE20-713850-AF405L$485 / 100μlE20-713850-AF546$485 / 100μlE20-713850-AF594$485 / 100μlE20-713850-AF610$485 / 100μlE20-713850-AF635$485 / 100μlE20-713850-AF647$485 / 100μlE20-713850-AF680$485 / 100μlE20-713850-AF700$485 / 100μlE20-713850-AF750$485 / 100μlE20-713850-AF790$485 / 100μlE20-713850-APC$485 / 100μlE20-713850-PE$485 / 100μlE20-713850-Cy3$485 / 100μlE20-713850-Cy5$485 / 100μlE20-713850-Cy5.5$485 / 100μlE20-713850-Cy7$485 / 100μlE20-713850-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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