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DHRS4 Polyclonal Antibody
Human;Rat;Mouse;
WB;IHC-p;IF(paraffin section);ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Gene NameDHRS4
Product Information
Protein NameDehydrogenase/reductase SDR family member 4
Human Gene Id10901
Human Swiss Prot NoQ9BTZ2
Mouse Swiss Prot NoQ99LB2
SpecificityDHRS4 Polyclonal Antibody detects endogenous levels of DHRS4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDHRS4; Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD
Molecular Weight27572Da
Observed Band(KD)32-34
Functioncatalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,function:Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.,miscellaneous:Inhibited by kaempferol, quercetin, genistein and myristic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subcellular location:Isoform 1 is peroxisomal, while isoform 4 is not.,subunit:Homotetramer.,tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protei
Subcellular Location[Isoform 1]: Peroxisome . Isoform 4 is not peroxisomal. .; [Isoform 7]: Nucleus .
Expression[Isoform 1]: Predominantly expressed in normal cervix (at protein level). ; [Isoform 4]: Expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). ; [Isoform 5]: Expressed in a few neoplastic cervical tissues. ; [Isoform 6]: Expressed in a few neoplastic cervical tissues. ; [Isoform 8]: High expression in liver.
ImmunogenThe antiserum was produced against synthesized peptide derived from human DHRS4. AA range:191-240
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Backgroundcatalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,function:Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.,miscellaneous:Inhibited by kaempferol, quercetin, genistein and myristic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subcellular location:Isoform 1 is peroxisomal, while isoform 4 is not.,subunit:Homotetramer.,tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoforms 5 and 6 are expressed in a few neoplastic cervical tissues.,
Western Blot analysis of HepG2 cells Immunohistochemistry using DHRS4 Polyclonal Antibody breast carcinoma diluted at 1:2000. the right is
analysis of paraffin-embedded human tissue, using DHRS4 Antibody. The picture on blocked with the synthesized peptide.
Conjugated Antibody
This product is also available conjugated. Format: E20-713849-Conjugate. Price: $485 / Size: 100μl.
E20-713849-FITC$485 / 100μlE20-713849-Biotin$485 / 100μlE20-713849-HRP$485 / 100μlE20-713849-AP$485 / 100μlE20-713849-AF350$485 / 100μlE20-713849-AF405M$485 / 100μlE20-713849-AF488$485 / 100μlE20-713849-AF514$485 / 100μlE20-713849-AF532$485 / 100μlE20-713849-AF555$485 / 100μlE20-713849-AF568$485 / 100μlE20-713849-AF405S$485 / 100μlE20-713849-AF405L$485 / 100μlE20-713849-AF546$485 / 100μlE20-713849-AF594$485 / 100μlE20-713849-AF610$485 / 100μlE20-713849-AF635$485 / 100μlE20-713849-AF647$485 / 100μlE20-713849-AF680$485 / 100μlE20-713849-AF700$485 / 100μlE20-713849-AF750$485 / 100μlE20-713849-AF790$485 / 100μlE20-713849-APC$485 / 100μlE20-713849-PE$485 / 100μlE20-713849-Cy3$485 / 100μlE20-713849-Cy5$485 / 100μlE20-713849-Cy5.5$485 / 100μlE20-713849-Cy7$485 / 100μlE20-713849-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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