Product Information
Protein NameDehydrogenase/reductase SDR family member 2
Human Gene Id10202
Human Swiss Prot NoQ13268
SpecificityDHRS2 Polyclonal Antibody detects endogenous levels of DHRS2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDHRS2; Dehydrogenase/reductase SDR family member 2; Dicarbonyl reductase HEP27; Protein D
Molecular Weight27439Da
Observed Band(KD)27
Functionfunction:May inhibit cell replication either by catalyzing the oxidation of estrogen and androgen or by converting cortisone in cortisol.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
Subcellular LocationMitochondrion matrix. Nucleus. A minor fraction of the protein is translocated from the mitochondria to the nucleus, after cleavage of the targeting signal.
ExpressionWidely expressed, with highest levels in liver and kidney, followed by heart, spleen, skeletal muscle and placenta. In hemopoietic cells, expressed in dendritic cells, but not in monocytes, macrophages, granulocytes, nor in B and T lymphocytes.
Backgroundfunction:May inhibit cell replication either by catalyzing the oxidation of estrogen and androgen or by converting cortisone in cortisol.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,