Product Information
Molecular Weight51400Da
Protein NameDNA polymerase delta subunit 3
Human Gene Id10714
Human Swiss Prot NoQ15054
Mouse Swiss Prot NoQ9EQ28
SpecificityDNA pol δ3 Polyclonal Antibody detects endogenous levels of DNA pol δ3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePOLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66
Observed Band(KD)51
Functionfunction:Required for optimal DNA polymerase delta activity.,subunit:Heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. Interacts with POLD2. Interacts with PCNA.,
Subcellular Locationnucleus,nucleoplasm,mitochondrion,delta DNA polymerase complex,
ExpressionBone marrow,Brain,Duodenum,Embryonic kidney,Epithelium,Lymp
BackgroundDNA polymerase delta 3, accessory subunit(POLD3) Homo sapiens This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012],