Product Information
Molecular Weight37681Da
Protein NameMeiotic recombination protein DMC1/LIM15 homolog
Human Gene Id11144
Human Swiss Prot NoQ14565
Mouse Gene Id13404
Mouse Swiss Prot NoQ61880
SpecificityDmc1 Polyclonal Antibody detects endogenous levels of Dmc1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDMC1; DMC1H; LIM15; Meiotic recombination protein DMC1/LIM15 homolog
Functionfunction:May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.,similarity:Belongs to the recA family. DMC1 subfamily.,similarity:Contains 1 HhH domain.,subunit:Interacts with the MND1-PSMC3IP heterodimer (By similarity). Double stacked ring-shaped homooctamer.,
Subcellular Locationchromosome, telomeric region,condensed nuclear chromosome,nucleus,nucleoplasm,chromosome,
ExpressionOvary,Testis,Thymus,
BackgroundDNA meiotic recombinase 1(DMC1) Homo sapiens This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],